The ARL3 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ARL3. This antibody recognizes Human, Mouse, and Rat antigen. The ARL3 Polyclonal Antibody has been validated for the following applications: ELISA, and Western Blot.
Description
ADP-ribosylation factor-like 3 is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL3 binds guanine nucleotides but lacks ADP-ribosylation factor activity. Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase-activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms